Core patent Europe was revoked! Can Johnson & Johnson’s heavy psoriasis is better-selling drugs?

On February 28, 2020, EuropeanPatentOffice, EPO decided to revoke European patents (hereinafter referred to as EP1896073B1) numbered 1896073, and currently exceeded the appeal period, the revocation decision has taken effect. EP1896073B1 Patent title is “Anti-IL-23 daientibodies, Compositions, Methodsanduses” (anti-IL-23 antibody, composition, method and use), patentee: Janssenbiotech, Inc. This patent is one of the core patents of guselkumab in psoriasis drugs.

Request to revoke EP1896073B1 is the three famous companies: Boehringeringer, Yingeharmagmbh & Co. KG, Mercksharp & dohmecorp.), ElilillyandCompany.

Patent EP1896073B1 is submitted to the application on the 30th of 2006, and the European Patent Office authorized by the European Patent Office on March 06, 2013. In December 2013, Boehlinger, Germany, and The rituals have been proposed (in the invalid objection process, Mercure East and Silver propose a dismoximate). The reasons for submitting objections are based primarily on the European Patent Convention (EPC1973) Article 54 (novelty), Article 56 (Creativity) and Article 123 (2) (Modify Ultra Range).

EP1896073B1 Connect the chimeric, humanized, engineering, and human antibodies within the scope of the claims of the invention, and the protection range is relatively large. The patent has a total of 28 claims comprising three independent, respectively, respectively, and claims 7 and claim 13, respectively, interested readers can interpret themselves.

About Guselkumab (Gu Shiqi 单)

Guselkumab (Chinese Name: Gu Shiiyou Anti-Cermatic Name: Tremfya / Teña) is a US Johnson & Delivery R & D. 23 Humanized monoclonal antibodies in action. July 2017 FDA approved Tremfya treatment medium severe plaque chilly chillyfish disease. In February 2019, the FDA was approved by the self-injection version for the treatment of adult plaque chin. In China, Gu Shiqi monk has been included in 2018, “The first batch of clinical urgent needs of the new drug list”, submitted to the listing application in June 2019, only 6 months of approved in December 2019, and March 2020 officially listed in China.

Up to now, TreMfya has been approved in many countries and regions around the world, used in the treatment of adults in moderate to severe plaque psoriasis.

Tremfya (Guselkumab) Global sales is $ 544 million in 2018, 2019 global sales reached US $ 1012 million, ranked 148th in the global drug sales TOP200. According to Evaluatepharma, Tremfya to 2023 sales will exceed $ 3 billion, and the market prospect is broad.

Conclusion:

With the increase in Guselkumab (Gu Shiji Swings), I believe that it will be increasingly concerned by the imitation drug. Although European patent EP1896073B1 is considered to be invalid, it is still in an effective state in China’s admiral patents and other core patents, and the patented barriers still exist.

As a pharmaceutical enterprise, in the process of project project and research and development, the patents must be fully investigated, and according to foreign intellectual property development trends and competitors research and development, the product is evangered to avoid them.

references:

Medicine patent

European Patent Office

Xi’an Yangson official website

Top200drugs by retail salesin2019

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